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The principal cytochrome P450 isoenzyme associated appears to get CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Somewhere around 85% of the oral dose appears while in the urine within 24 several hours of administration, most given that the glucuronide conjugate, with smaller amounts of other conjugates and unchanged drug (see OVERDOSAGE) for tox